Formulation and evaluation of organic handwash prepared from herbal extracts
DOI:
https://doi.org/10.52756/ijerr.2022.v29.003Keywords:
Aloe vera, Antimicrobial activity, Herbal handwash, Hygiene, Organic handwash, TulsiAbstract
The scientific study linked to the physical, chemical, biological, and structural characterization of drugs along with their history of cultivation, collection and preparation for marketing and preservation, is defined as pharmacognosy. The cardinal routes of the entry of various infections into our body are our hands. The infection caused thereby causes a spectrum of diseases, especially in children. To get rid of such infections, regular washing of hands after specific time intervals holds imperative cognizance of getting rid of such infectious diseases. The handwash available in the local markets is mainly composed of various chemical compounds which might pose several threats to our skin. In this notion, the search for alternate components for handwash preparation that are organic in nature and do not cause any damage to our skin has been in the research limelight for the past few years. Accordingly, in this research, an attempt has been made to prepare a skin-friendly handwash containing the essential extracts of various ingredients like Aloe vera, turmeric, honey, tulsi, lemon, etc., and thereby their antimicrobial and antiseptic efficacy were evaluated. The basis of the evaluation was set using multivariate criteria like odour, colour, viscosity, pH, foam height and retention, and grittiness. Finally, the skin irritation test was also carried out along with a few other parameters to draw conclusions regarding the suitability of the handwash for human usage. The obtained results were found within the desired ranges without the presence of any adverse side effects. Thus, the proposed scheme of this study may be regarded as an excellent approach to combat the harmful effects of commercial chemicals containing handwash and, thereby, will be beneficial to various stakeholders.
References
Afsar, Z. & Khanam, S. (2016). Formulation and Evaluation of Polyherbal Soap and Hand Sanitizer, International Research Journal of Pharmacy, 7(8), 54-57. https://doi.org/10.7897/2230-8407.07896
Bahuguna, M., & Kashyap, S. (2016). Formulation and Evaluation of Hand Wash. World Journal of Pharmaceutical Research. 5(7), 1559 – 1577.
Bayot, M. L., & Bragg, B. N. (2021). Antimicrobial Susceptibility Testing. In StatPearls. Stat Pearls Publishing.
Bhadane, S., Takarkhede, S., Kakade, P., Jaiswal, S., Kanaujiya, S., & Khan, A. (2022). Formulation and evaluation of herbal hand sanitizer. World Journal of Pharmaceutical Research, 11(4), 695-705
Bjerke N. B. (2004). The evolution: Handwashing to hand hygiene guidance. Critical Care Nursing Quarterly, 27(3), 295–307. https://doi.org/10.1097/00002727-200407000-00007
Bondi, C. A., Marks, J. L., Wroblewski, L. B., Raatikainen, H. S., Lenox, S. R., & Gebhardt, K. E. (2015). Human and Environmental Toxicity of Sodium Lauryl Sulfate (SLS): Evidence for Safe Use in Household Cleaning Products. Environmental Health Insights, 9, 27–32. https://doi.org/10.4137/EHI.S31765
Chirani, M. R., Kowsari, E., Teymourian, T., & Ramakrishna, S. (2021). Environmental impact of increased soap consumption during COVID-19 pandemic: Biodegradable soap production and sustainable packaging. The Science of the Total Environment, 796, 149013. https://doi.org/10.1016/j.scitotenv.2021.149013
Cohen M. M. (2014). Tulsi-Ocimum sanctum: A herb for all reasons. Journal of Ayurveda and Integrative Medicine, 5(4), 251–259. https://doi.org/10.4103/0975-9476.146554
Garner, J. S., & Favero, M. S. (1986). CDC Guideline for Handwashing and Hospital Environmental Control, 1985. Infection Control: IC, 7(4), 231–243. https://doi.org/10.1017/s0195941700084022.
Hanai, H., Sugimoto, K. (2009). Curcumin has bright prospects for the treatment of inflammatory bowel disease. Curr. Pharm. Des., 15, 2087–2094. https://doi.org/10.2174/138161209788489177
Joshi, M. G., Kamat, D. V., & Kamat, S. D. (2008). Evaluation of herbal hand washes formulation. Journal of Natural Product Radiance, 7(5): 423-25.
Klimek-Szczykutowicz, M., Szopa, A., & Ekiert, H. (2020). Citrus limon (Lemon) Phenomenon-A Review of the Chemistry, Pharmacological Properties, Applications in the Modern Pharmaceutical, Food, and Cosmetics Industries, and Biotechnological Studies. Plants (Basel, Switzerland), 9(1), 119. https://doi.org/10.3390/plants9010119
Mohebitabar, S., Shirazi, M., Bioos, S., Rahimi, R., Malekshahi, F., & Nejatbakhsh, F. (2017). Therapeutic efficacy of rose oil: A comprehensive review of clinical evidence. Avicenna Journal of Phytomedicine, 7(3), 206–213.
Pahurkar, S., Narkhede, M., & Kardile, M. (2022). Formulaton and Evaluation of Herbal Handwash Gel from Jasmine Leaf Extract with Antimicrobial Activity. International Journal of Pharmaceutical Research and Applications. 7(4), 1163-1169.
https://doi.org/10.35629/7781-070411631169
Patankar, R. S., & Chandak, N. (2018). Formulation of Herbal Sanitizers and Determining Their Antimicrobial Activities Against Skin Pathogens. International Journal of Innovative Science and Research Technology. 3(8), 169-177.
Patil, S.S., Mane, Y.J., & Mohite, S. K. (2017). Formulation and Evaluation of Herbal Shampoo Powder. International Journal of Pharma and Chemical Research, 3(3), 939-946
Powar, P.V., Bhandari, N.R, Arya, A., & Sharma, P.H. (2015). Formulation and Evaluation of Poly Herbal Anti-Bacterial Gel Based Hand Wash. International Journal of Pharmaceutical Sciences Review and Research, 33(1), 79 – 82.
Ravi, K., Pratibha, M. D., & Kolhapure, S. A., (2005). Evaluation of the antimicrobial efficacy and safety of Pure Hands as a hand sanitizer. Indian Journal of Clinical Practice. 15(10), 19-27.
Shaloo, S. S., Singh, S., Verma, S., Tiwari, R. K., & Tripathi, D. (2017). Formulation and Development of Mint containing Herbal Hand Sanitizer. European Journal of Pharmaceutical and Medical Research, 11, 454 - 457.
Surjushe, A., Vasani, R., & Saple, D. G. (2008). Aloe vera: a short review. Indian Journal of Dermatology, 53(4), 163–166. https://doi.org/10.4103/0019-5154.44785
Tabassum, N., & Hamdani, M. (2014). Plants used to treat skin diseases. Pharmacognosy Reviews, 8(15), 52–60. https://doi.org/10.4103/0973-7847.125531
Terker, N. N., Sharma, A. V. K., Tekawade, J. A., Momin, T. A., & Mukhid, S. E. S. (2021). Formulation and Evaluation of Polyherbal Hand Wash (Gel). International Journal of Science and Research. 10(8), 1213-1219.
Wolfe, M. K., & Lantagne, D. S. (2017). A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens. Journal of Visualized Experiments, 124, 55604. https://doi.org/10.3791/55604